Department of Chemistry, Physics, and Atmospheric Sciences – CHEMISTRY
College of Science, Engineering, and Technology

Chemistry is the study of how matter behaves at its most basic level. The central science, chemistry, is involved in everything that we do. Its applications stretch across all areas of life, including medicine, engineering and agriculture.

Yi-Ming Liu

Professor
	1400 J. R. Lynch Street, P.O. Box 17910 Jackson, MS39217-0510 Physical location: John A. Peoples Science Building Office: NSB Room #537 *Contact:* E-mail: yiming.liu@jsums.edu Tel: (601) 979-3491 Fax: (601) 979-3674
Teaching
Analytical Chemistry CHEM 320 General Chemistry CHEM 141 &142 Spectroscopic Methods CHEM 729
Research Interests:
*Analytical Chemistry:* Research in the Liu group is focused on the development of novel analytical methods for sensitive and selective bioassays. A wide range of instrumental techniques including bioluminescence, CE, HPLC, GC-MS/MS, CE-MS/MS, and HPLC-MS/MS are involved. In a particular project funded by National institutes of Health, the group is developing chiral separations based on microchip electrophoresis with mass spectrometric detection. These methods are developed for chiral single cell analysis as applied in metabolic studies of biomedically interesting compounds such as neurotransmitters, environmental toxins, and pharmaceutical chemicals.
Selected publications (click here for full list)
X Li, S Zhao, YM Liu, Evaluation of a microchip electrophoresis-mass spectrometry platform deploying a pressure-driven make-up flow, Journal of Chromatography A, 1285, 159-164, 2013. S Zhao, J Liu, Y Huang, YM Liu, Introducing chemiluminescence resonance energy transfer into immunoassay in a microfluidic format for an improved assay sensitivity, Chem. Commun. 48 (5), 699-701, 2011. Y Huang, S Zhao, H Liang, ZF Chen, YM Liu, Multiplex detection of endonucleases by using a multicolor gold nanobeacon, Chemistry-A European Journal 17 (26), 7313-7319, 2011. L.S. Qing, Y. Xue, Y. Zheng, J. Xiong, X. Liao, L.S. Ding, B.G. Li, Y.M. Liu “Ligand fishing from Dioscorea nipponica extract using human serum albumin functionalized magnetic nanoparticles,” J. Chromatogr. A 2010, 1217: 4663-4668. S. Zhao, Y. Huang, R. Liu, M. Shi, Y. M. Liu “A Nonenzymatic Chemiluminescent Reaction Enabling Chemiluminescence Resonance Energy Transfer to Quantum Dots,” Chemistry–A European J. 2010, 16: 6142-6145. Y. Huang, S. Zhao, M. Shi, Y. M. Liu* “Chemiluminescent immunoassay of thyroxine enhanced by microchip electrophoresis,” Anal. Biochem. 2010, 399: 72-77. PMID: 19961826. S. Zhao, Y. Huang, M. Shi, R. Liu, Y. M. Liu* “Chemiluminescence Resonance Energy Transfer-based Detection for Microchip Electrophoresis,” Anal. Chem. 2010, 82: 2036-2041. PMID: 20121202. S. Zhao, Y. Huang, Y. M. Liu* “Microchip electrophoresis with chemiluminescence detection for assaying ascorbic acid and amino acids in single cells,” J. Chromatogr. A 2009, 1216: 6746-51. S. Zhao, Y. Huang, M. Shi, Y. M. Liu* “Quantification of biogenic amines by microchip electrophoresis with chemiluminescence detection,” J. Chromatogr. A 2009, 1216: 5155–59. S. Zhao, X. Li, Y. M. Liu* “Integrated microfluidic system with chemiluminescence detection for single cell analysis after intracellular labeling,” Anal. Chem. 2009, 81: 3873–78.